Cica-derived exosomes paired with PDRN, glutathione, and a five-form vitamin C complex — a premium treatment cream for radiance, even tone, and the kind of skin renewal Korean dermatologists target post-procedure. Liposome-encapsulated for stability and deeper delivery.
A premium treatment cream formulated around four clinical actives: a Cica-derived exosome system for cellular signaling, PDRN for skin-quality and barrier support, glutathione for antioxidant brightening, and a multi-molecular vitamin C complex (five forms) for radiance and tone evenness. Active ingredients are protected within 0.1–0.4 µm liposomes — encapsulation that's there for ingredient stability and deeper skin penetration, not as a marketing flourish.
Designed for mature skin, post-procedure recovery, and anyone targeting radiance and tone evenness. Works best as the final step of an evening routine. CURENEX clinical-tested this on 30 women aged 30 to 60 over 12 weeks, twice daily — visible improvements in brightness, firmness, hydration, and texture, with no irritation reported.
After cleansing and any treatment ampoules, take a pea-sized amount and warm between fingertips. The warmth helps the cream emulsify properly into skin.
Press gently into skin from the center of the face outward. Don't rub — press. Korean technique, and it actually matters for absorption. Apply more on areas of dullness or pigmentation.
Use in the evening, or AM and PM for more intensive results. Always pair with broad-spectrum SPF during the day — vitamin C and glutathione both work better under sun protection.
Patch test if you're new to vitamin C. The multi-molecular blend is well-tolerated, but sensitive skin should start once daily before going twice.
CURENEX positions this as a Centella-derived exosome system delivered through their liposome encapsulation. Exosomes are extracellular signaling vesicles that carry plant peptides and bioactive cargo — the topical version of the cellular communication that the technology is built around. The cream also contains traditional Centella Asiatica leaf extract for the calm, anti-inflammatory base Korean dermatology relies on.
The same skin-quality polynucleotide active used clinically in Rejuran injections, formulated at topical concentration. PDRN supports cell viability, extracellular matrix formation, and fibroblast activity in published research — the mechanisms behind the skin-renewal effects Korean dermatology uses PDRN for. In a cream this rich, the PDRN gets the extended contact time it needs to work.
Five forms of vitamin C, each chosen for a different role: Ascorbic Acid (potent antioxidant, reduces pigmentation), 3-O-Ethyl Ascorbic Acid (highly stable, strengthens barrier), Sodium Ascorbyl Phosphate (gentle, promotes collagen synthesis), Ascorbyl Glucoside (long-acting brightening), Ascorbyl Palmitate (lipid-soluble, deeper layer protection). Multi-molecular delivery means coverage across skin depths without the irritation that pure L-ascorbic alone causes.
The molecule Korean clinics inject for brightening — formulated here for topical delivery via the liposome system. Glutathione is the body's master antioxidant; topically, it works on the same melanogenesis pathway that gives Korean brightening treatments their reputation. Pairs synergistically with vitamin C — both are antioxidants, but they regenerate each other in the skin to extend the active life of both.
Water, Butylene Glycol, Glycerin, Niacinamide, Cetyl Ethylhexanoate, Hydrogenated Polydecene, Diisostearyl Malate, Cetearyl Olivate, Boron Nitride, Vinyl Dimethicone, Polyglyceryl-3 Methylglucose Distearate, Sorbitan Olivate, 1,2-Hexanediol, Hydroxyacetophenone, Ammonium Acryloyldimethyltaurate/VP Copolymer, Glyceryl Stearate SE, Glyceryl Stearate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyisobutene, Allantoin, Glyceryl Glucoside, Ethylhexylglycerin, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Caprylyl Glycol, Ethylhexyl Olivate, Adenosine, Sodium Acrylates Copolymer, Sodium Phytate, Sorbitan Oleate, Caprylyl/Capryl Glucoside, Polyglyceryl-4 Oleate, Glutathione, Hydrogenated Lecithin, Ascorbic Acid, 3-O-Ethyl Ascorbic Acid, Rosa Damascena Extract, Sodium DNA, Sodium Ascorbyl Phosphate, Ascorbyl Glucoside, Ascorbyl Palmitate, Disodium EDTA, Centella Asiatica Leaf Extract, Octyldodecanol, Limonene, Linalool.
INCI as published in the CURENEX manufacturer brochure. Always confirm against the label of the product you receive.
Direct ordering opens Summer 2026. Get notified the day this SKU is available — early-access pricing for list members.
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